Thursday, January 06, 2011

New Directions



I met with my oncologist at Seattle Cancer Care today.  As a result of our discussion and following a review of the 29 page consent form (for which I was very glad to have friends Diane and Anne there to help with that), I have signed up for a trial.  The drug is Protocol No. CA2100001 (MDX1105-01), sponsored by Bristol Meyers.  It operates by freeing up the body's immune system to fight the cancer.  My physician said that initially he was sceptical about this idea/drug but 2 out 3 of his patients that he's enrolled in the trial have had substantial success.  And although that is not statistically significant overall, he thinks it portends well for me. 

It doesn't matter if I am EGFR negative and don't have the ALK arrangement for this drug.  I need to have a brain MRI to establish that there are no brain metastases and an ECG to assess my heart's condition, but assuming I pass those tests, I will be enrolled in the trial, which consists of administration of the drug intravenously every two weeks. 

So fingers crossed.  Side effects include diarrhea, joint pain, rash, and other  autoimmune reactions, but I will be closely monitored.  Nothing is for certain in life, but my experience as a lab rat will hopefully help in the development of effective cancer treatments.

6 comments:

Anonymous said...

I'm glad that there is a new and promising option for you--and I'm sending you my best wishes, prayers, and hugs!

--Janet B.

odp said...

What Janet B. said!
Olive

Dan Matyola said...

I think that you and your physician have made a good choice. As I said, you are a fighter, and you will get through this.

Keep your positive attitude, and we will keep you in our thoughts and prayers.

Dan

Amanda said...

When you alluded to your upcoming experience as a lab rat, I was trying to remember if the lab rats are the ones that are supposed to survive a nuclear attack!! If so, that bodes well for your new treatment.

I hope the rats lead the way!!!

Dorothy & Michael said...

This is wonderful and very encouraging news! I'll be watching for more updates as the days progress, and wish you lots of healthy days ahead!

Courtney said...

only research cures cancer! you are doing a GREAT thing - a lot of people are scared of clinical trials but there is no reason to be - they are closely monitored and often save lives.